GPR75 antibody (AA 151-250) (Cy7)
Quick Overview for GPR75 antibody (AA 151-250) (Cy7) (ABIN6985975)
Target
See all GPR75 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 151-250
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Purpose
- GPCR GPR75 Polyclonal Antibody, Cy7 Conjugated
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Cross-Reactivity
- Mouse
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Predicted Reactivity
- Human
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human GPCR GPR75
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Isotype
- IgG
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Application Notes
- WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
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Alternative Name
- GPR75
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Background
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Synonyms: Probable G-protein coupled receptor 75, GPR75,
Background: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
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Gene ID
- 10936
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UniProt
- O95800
Target
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