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ADC antibody (AA 51-150) (Cy7)

ADC Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN6986013
  • Target See all ADC Antibodies
    ADC (Arginine Decarboxylase (ADC))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 21
    • 19
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADC antibody is conjugated to Cy7
    Application
    • 21
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ODCp
    Isotype
    IgG
    Top Product
    Discover our top product ADC Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ADC (Arginine Decarboxylase (ADC))
    Alternative Name
    ODCp (ADC Products)
    Synonyms
    MGC134604 antibody, azi2 antibody, odc2 antibody, odc-p antibody, odc1l antibody, xodc2 antibody, ADC antibody, AZI2 antibody, ODC-p antibody, ODC1L antibody, 4933429I20Rik antibody, AZIN2 antibody, Azi2 antibody, B930082O19 antibody, Odcp antibody, RGD1564776 antibody, odc1-b antibody, arginine decarboxylase antibody, antizyme inhibitor 2 antibody, biosynthetic arginine decarboxylase SpeA antibody, biosynthetic arginine decarboxylase SpeA (ADC) antibody, pyruvoyl-dependent arginine decarboxylase antibody, antizyme inhibitor 2 S homeolog antibody, AZIN2 antibody, azin2 antibody, adc antibody, speA antibody, Mrub_2839 antibody, MMAH_RS09440 antibody, Arnit_1968 antibody, Mesil_3114 antibody, Trad_0080 antibody, Spirs_3255 antibody, LOC100233080 antibody, Azin2 antibody, azin2.S antibody
    Background

    Synonyms: Antizyme inhibitor 2, AZIN2, Arginine decarboxylase, ADC, ARGDC, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODC-p, AZIN2, ADC, KIAA1945, ODCP

    Background: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240). Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking (PubMed:20188728).

    Gene ID
    113451
    UniProt
    Q96A70
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