OPRD1 antibody (AA 81-180) (FITC)

Catalog No. ABIN6986630

The Rabbit Polyclonal anti-OPRD1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect OPRD1 in samples from Human, Mouse and Rat.

Quick Overview for OPRD1 antibody (AA 81-180) (FITC) (ABIN6986630)

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRD1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-OPRD1 Antibody (FITC)

Binding Specificity: AA 81-180

Specificity: This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79 % non-contiguous sequence similarity.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPRD1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Alternative Name: Delta-type opioid receptor

Background:

Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gene ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus