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CD209b Antigen (CD209B) (AA 51-150) antibody (FITC)

CD209B Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN6986926
  • Target See all CD209b Antigen (CD209B) Antibodies
    CD209b Antigen (CD209B)
    Binding Specificity
    AA 51-150
    Reactivity
    Mouse
    Host
    • 14
    • 5
    • 5
    Rabbit
    Clonality
    • 14
    • 10
    Polyclonal
    Conjugate
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    FITC
    Application
    • 14
    • 12
    • 12
    • 8
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CD209b
    Isotype
    IgG
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  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD209b Antigen (CD209B)
    Alternative Name
    CD209b (CD209B Products)
    Synonyms
    1810030I22Rik antibody, OtB7 antibody, SIGNR1 antibody, mSIGNR1 antibody, CD209b antigen antibody, Cd209b antibody
    Background

    Synonyms: SIGN Related 1, CD209 antigen like protein B, CD209b antigen, DC SIGN related protein 1, DC SIGNR1, OtB7

    Background: SIGN R1 is a specific marker for the identification of macrophage subpopulations present in the marginal zone of spleen (the so-called marginal zone macrophages (MZM)), in the lymph node medulla, and in some strains, in the peritoneal cavity. MZM of the spleen are involved in the clearance of polysaccharides. Mouse SIGN R1 is a C type lectin, like DC SIGN which is expressed on Human dendritic cells (DCs). However, Mmouse SIGN R1 itself is not expressed on DCs. SIGN R1 exists in an aggregated form, resistant to dissociation into monomers upon boiling in SDS under reducing conditions. SIGN R1 mediates the uptake of encapsulated organisms and may be an important mediator for the uptake of microbes in both spleen and lymph node, particularly through the recognition of microbial polysaccharides.

    Gene ID
    69165
    UniProt
    Q8CJ91
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