Oncostatin M Receptor antibody (AA 571-670) (FITC)

Catalog No. ABIN6987274

This Rabbit Polyclonal antibody specifically detects Oncostatin M Receptor in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for Oncostatin M Receptor antibody (AA 571-670) (FITC) (ABIN6987274)

Target: Oncostatin M Receptor (OSMR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oncostatin M Receptor antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Oncostatin M Receptor Antibody (FITC)

Binding Specificity: AA 571-670

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OSMR

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Oncostatin M Receptor

Target: Oncostatin M Receptor (OSMR)

Alternative Name: OSMR

Background:

Synonyms: Oncostatin M receptor, Oncostatin M specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, Oncostatin-M-specific receptor, beta, OSMRB, MGC140467, MGC150626, MGC150627, MGC75127.

Background: Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.

Gene ID: 9180

UniProt: Q99650

Pathways: JAK-STAT Signaling, Growth Factor Binding