Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LNX1 antibody (AA 101-200) (HRP)

This anti-LNX1 antibody is a Rabbit Polyclonal antibody detecting LNX1 in ELISA, IHC (p) and IHC (fro). Suitable for Mouse and Rat.
Catalog No. ABIN6987591

Quick Overview for LNX1 antibody (AA 101-200) (HRP) (ABIN6987591)

Target

See all LNX1 Antibodies
LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivity

  • 24
  • 19
  • 18
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Mouse, Rat

Host

  • 32
  • 6
Rabbit

Clonality

  • 35
  • 3
Polyclonal

Conjugate

  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LNX1 antibody is conjugated to HRP

Application

  • 13
  • 13
  • 12
  • 11
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 14
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Cross-Reactivity

    Mouse, Rat

    Predicted Reactivity

    Human,Cow,Sheep,Horse

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human LNX1

    Isotype

    IgG
  • Application Notes

    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    LNX1 (Ligand of Numb-Protein X 1 (LNX1))

    Alternative Name

    LNX1

    Background

    Synonyms: E3 ubiquitin protein ligase LNX, Ligand of Numb protein X 1, Ligand of numb protein X 1 E3 ubiquitin protein ligase, LNX, LNX1, LNX1_HUMAN, MPDZ, Multi PDZ domain containing protein E3 ubiquitin protein ligase LNX, Numb binding protein 1, PDZ domain-containing ring finger protein 2, PDZRN2.

    Background: Lnx1 is a membrane-bound protein that is involved in signal transduction and protein interactions. Lnx1 is an E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Lnx1 mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.

    Gene ID

    84708

    UniProt

    Q8TBB1
You are here:
Chat with us!