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TTC3 antibody (AA 251-350) (HRP)

TTC3 Reactivity: Mouse, Rat IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN6987799
  • Target See all TTC3 Antibodies
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    AA 251-350
    Reactivity
    • 5
    • 3
    • 2
    Mouse, Rat
    Host
    • 5
    • 2
    Rabbit
    Clonality
    • 6
    • 1
    Polyclonal
    Conjugate
    • 6
    • 1
    This TTC3 antibody is conjugated to HRP
    Application
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RNF105
    Isotype
    IgG
    Top Product
    Discover our top product TTC3 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Alternative Name
    RNF105 (TTC3 Products)
    Synonyms
    DCRR1 antibody, RNF105 antibody, TPRDIII antibody, 2610202A04Rik antibody, AA409221 antibody, D16Ium21 antibody, D16Ium21e antibody, TPRD antibody, mKIAA4119 antibody, TTC3 antibody, tetratricopeptide repeat domain 3 antibody, E3 ubiquitin-protein ligase TTC3 antibody, TTC3 antibody, Ttc3 antibody, LOC100562480 antibody
    Background

    Synonyms: DCRR1, E3 ubiquitin protein ligase TTC3, E3 ubiquitin-protein ligase TTC3, Protein DCRR1, RING finger protein 105,Tetratricopeptide repeat protein 3 (TPR repeat protein D), Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, TPRD, TPRDI, TPRDII, TPRDIII, TTC3, TTC3_HUMAN.

    Background: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

    Gene ID
    7267
    UniProt
    P53804
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