PEG3 antibody (AA 1011-1110) (HRP)

Catalog No. ABIN6987828

This anti-PEG3 antibody is a Rabbit Polyclonal antibody detecting PEG3 in IHC (p). Suitable for Human.

Quick Overview for PEG3 antibody (AA 1011-1110) (HRP) (ABIN6987828)

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PEG3 Antibody (HRP)

Binding Specificity: AA 1011-1110

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEG3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3

Background:

Synonyms: Paternally-expressed gene 3 protein, Zinc finger and SCAN domain-containing protein 24, Kruppel-type zinc finger protein, paternally expressed 3, Paternally expressed gene 3, PEG3 protein, Pw1, Zn-finger protein Pw1, PEG3_HUMAN, Paternally-expressed gene 3 protein.

Background: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. Possesses a tumor suppressing activity in glioma cells.

Gene ID: 18616

UniProt: Q9GZU2