RNF43 antibody (AA 401-500) (HRP)

Catalog No. ABIN6987925

This Rabbit Polyclonal antibody specifically detects RNF43 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RNF43 antibody (AA 401-500) (HRP) (ABIN6987925)

Target: RNF43 (Ring Finger Protein 43 (RNF43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF43 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RNF43 Antibody (HRP)

Binding Specificity: AA 401-500

Purpose: RNF43 Polyclonal Antibody, HRP Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF43

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNF43

Target: RNF43 (Ring Finger Protein 43 (RNF43))

Alternative Name: RNF43

Background:

Synonyms: RNF124, Ring finger protein 43, URCC, RNF43_HUMAN, E3 ubiquitin-protein ligase RNF43, RING finger protein 43.

Background: RNF43 is a probable E3 ubiquitin-protein ligase that promotes cell growth and is upregulated in colon cancer. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Gene ID: 54894

UniProt: Q68DV7

Pathways: WNT Signaling