FAM134B antibody (AA 210-310) (PE)

Catalog No. ABIN6988325

The Rabbit Polyclonal anti-FAM134B antibody is suitable to detect FAM134B in samples from Human, Mouse and Rat. It has been validated for WB and FACS.

Quick Overview for FAM134B antibody (AA 210-310) (PE) (ABIN6988325)

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM134B antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-FAM134B Antibody (PE)

Binding Specificity: AA 210-310

Specificity: There is a chance that this protein will cross-react with MSL2 based on a 73 % non-sequential sequence similarity.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM134B

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM134B

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Alternative Name: FAM134B

Background:

Synonyms: JK1, JK-1, Reticulophagy receptor FAM134B, FAM134B

Background: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Gene ID: 54463

UniProt: Q9H6L5