CENPC1 antibody (PE)
Quick Overview for CENPC1 antibody (PE) (ABIN6988974)
Target
See all CENPC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- Purified by Protein A.
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Immunogen
- Recombinant human CENPC1 protein
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Isotype
- IgG
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Application Notes
- FCM 1:20-100
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Restrictions
- For Research Use only
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 4°C
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Expiry Date
- 12 months
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- CENPC1 (Centromere Protein C 1 (CENPC1))
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Alternative Name
- CENPC1
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Background
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Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Subcellular location: Nucleus
Synonyms: CENP-C 1, CENP-C, CENPC_HUMAN, CENPC1, Centromere autoantigen C, Centromere autoantigen C1, Centromere protein C 1, ICEN7, Interphase centromere complex protein 7, MIF2.
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Gene ID
- 1060
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UniProt
- Q03188
Target
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