LPAR1 antibody (AA 1-50)

Catalog No. ABIN6988995

This anti-LPAR1 antibody is a Rabbit Polyclonal antibody detecting LPAR1 in IHC (p). Suitable for Mouse.

Quick Overview for LPAR1 antibody (AA 1-50) (ABIN6988995)

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPAR1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LPAR1 Antibody

Binding Specificity: AA 1-50

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPA1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Alternative Name: LPA1

Background:

Synonyms: EDG 2, Endothelial Cell Differentiation Gene-2, Endothelial differentiation gene 2, Endothelial Differentiation Lysophosphatidic Acid G Protein Coupled Receptor 2, G10 protein homolog, GPCR 26, GPCR26, Gpcr91, Kdt2, LPA 1, LPA receptor 1, LPA receptor EDG2, LPA1, LPAR1, Lysophosphatidic acid receptor 1, Lysophosphatidic acid receptor EDG2, MGC105279, MGC29102, LPAR1_HUMAN.

Background: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.

Gene ID: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration