ATG13 antibody (AA 41-140)

Catalog No. ABIN6989064

This anti-ATG13 antibody is a Rabbit Polyclonal antibody detecting ATG13 in IHC (p). Suitable for Mouse and Rat.

Quick Overview for ATG13 antibody (AA 41-140) (ABIN6989064)

Target: ATG13 (Autophagy Related 13 (ATG13))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ATG13 Antibody

Binding Specificity: AA 41-140

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATG13

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ATG13

Target: ATG13 (Autophagy Related 13 (ATG13))

Alternative Name: ATG13

Background:

Synonyms: ATG13 autophagy related 13 homolog, ATG13_HUMAN, Autophagy related protein 13, Autophagy-related protein 13, FLJ20698, KIAA0652.

Background: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.

Gene ID: 9776

UniProt: O75143

Pathways: PI3K-Akt Signaling, Autophagy