TRIM56 antibody (AA 651-755)

Catalog No. ABIN6989197

This Rabbit Polyclonal antibody specifically detects TRIM56 in ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Rat.

Quick Overview for TRIM56 antibody (AA 651-755) (ABIN6989197)

Target: TRIM56 (Tripartite Motif Containing 56 (TRIM56))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM56 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-TRIM56 Antibody

Binding Specificity: AA 651-755

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF109/TRIM56

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TRIM56

Target: TRIM56 (Tripartite Motif Containing 56 (TRIM56))

Alternative Name: RNF109/TRIM56

Background:

Synonyms: A130009K11Rik, DKFZp667O116, E3 ubiquitin-protein ligase TRIM56, FLJ35608, Gm452, MGC37358, OTTMUSP00000027392, RING finger protein 109, RNF109, TRI56_HUMAN, Trim56, Tripartite motif containing protein 56, Tripartite motif-containing protein 56.

Background: E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA (By similarity).

Gene ID: 81844

UniProt: Q9BRZ2