MAGMAS antibody (AA 31-125)

Catalog No. ABIN6989298

The Rabbit Polyclonal anti-MAGMAS antibody (ABIN6989298) specifically detects MAGMAS in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. The antibody is reactive with Mouse samples.

Quick Overview for MAGMAS antibody (AA 31-125) (ABIN6989298)

Target: MAGMAS (PAM16) (Presequence Translocase-Associated Motor 16 Homolog (PAM16))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGMAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-MAGMAS Antibody

Binding Specificity: AA 31-125

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAM16

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MAGMAS

Target: MAGMAS (PAM16) (Presequence Translocase-Associated Motor 16 Homolog (PAM16))

Alternative Name: PAM16

Background:

Synonyms: CGI-136, MAGMAS, Magmas like protein, Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction, Mitochondria-associated granulocyte macrophage CSF-signaling molecule, Mitochondrial import inner membrane translocase subunit TIM16, PAM16, Presequence translocase-associated motor 16 homolog (S. cerevisiae), Presequence translocated-associated motor subunit PAM16, TIM16, TIM16_HUMAN, TIMM16.

Background: This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]

Gene ID: 51025

UniProt: Q9Y3D7