GRP78 antibody

Catalog No. ABIN6989444

The Mouse Monoclonal anti-GRP78 antibody has been validated for WB and IF (cc). It is suitable to detect GRP78 in samples from Human and Rat.

Quick Overview for GRP78 antibody (ABIN6989444)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRP78 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 12D9

Product Details anti-GRP78 Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human GRP78/Bip

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GRP78

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Alternative Name: GRP78/Bip

Background:

Synonyms: BIP, HSPA5, glucose regulated protein 78, 78 kDa glucose regulated protein, BIP, Endoplasmic reticulum lumenal Ca2+ binding protein grp78, FLJ26106, Glucose Regulated Protein 78 kDa, GRP 78, GRP78, Heat Shock 70 kDa Protein 5, HSPA 5, HSPA-5, HSPA5, Immunoglobulin Heavy Chain Binding Protein, MIF2, GRP78_HUMAN.

Background: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

Gene ID: 3309

UniProt: P11021

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling