DBF4 antibody

Catalog No. ABIN6989658

The Rabbit Monoclonal anti-DBF4 antibody (Clone 5H0) (ABIN6989658) specifically detects DBF4 in WB and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for DBF4 antibody (ABIN6989658)

Target: DBF4 (DBF4 Homolog (DBF4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DBF4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 5H0

Product Details anti-DBF4 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within N-terminal human DBF4.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DBF4

Target: DBF4 (DBF4 Homolog (DBF4))

Alternative Name: DBF4

Background:

Synonyms: Activator of S phase kinase antibody, ASK antibody, CHIF antibody, Chiffon homolog A antibody, DBF4 antibody, DBF4 homolog (S. cerevisiae) antibody, DBF4 homolog antibody, DBF4 type zinc finger containing protein 1 antibody, DBF4 zinc finger A antibody, DBF4 zinc finger antibody, DBF4, S. cerevisiae, homolog of antibody, DBF4-type zinc finger-containing protein 1 antibody, DBF4A antibody, DBF4A_HUMAN antibody, Dumbbell former 4, S. cerevisiae, homolog of antibody, OTTHUMP00000161661 antibody, Protein DBF4 homolog A antibody, ZDBF1 antibody, Zinc finger, DBF-type containing 1 antibody

Background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.

Gene ID: 10926

UniProt: Q9UBU7

Pathways: Mitotic G1-G1/S Phases, DNA Replication