GNA13 antibody

Catalog No. ABIN6989797

This Rabbit Polyclonal antibody specifically detects GNA13 in WB, IHC, IF (cc), IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GNA13 antibody (ABIN6989797)

Target: GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNA13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GNA13 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein of human GNA13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()
IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GNA13

Target: GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))

Alternative Name: GNA13

Background:

Synonyms: G alpha 13, GNA13, Guanine nucleotide binding protein alpha 13 subunit, GNA13_HUMAN.

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G Alpha subunits have been identified, these include G Alpha s, G Alpha i, G Alpha q and G Alpha 12/13. The two members of the fourth class of G Alpha subunit proteins, G Alpha 12 and G Alpha 13, are insensitive to ADP-ribosylation by pertussis toxin, share 67 % identity with each other and less than 45 % identity with other G Alpha subunits and are widely expressed in a broad range of tissue

Gene ID: 10672

UniProt: Q14344

Pathways: CXCR4-mediated Signaling Events