LDHB antibody
Quick Overview for LDHB antibody (ABIN6989822)
Target
See all LDHB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1).
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC() -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C for 12 months.
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Expiry Date
- 12 months
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- LDHB (Lactate Dehydrogenase B (LDHB))
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Alternative Name
- LDHB
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Background
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Synonyms: LDHB,HEL-S-281,LDH-B,LDH-H,LDHBD,TRG-5
Background: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
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Gene ID
- 3945
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UniProt
- P07195
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Pathways
- Warburg Effect
Target
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