PDCD10 antibody

Catalog No. ABIN6989859

This anti-PDCD10 antibody is a Rabbit Polyclonal antibody detecting PDCD10 in WB and IF. Suitable for Human and Mouse.

Quick Overview for PDCD10 antibody (ABIN6989859)

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PDCD10 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2).

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PDCD10

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Alternative Name: PDCD10

Background:

Synonyms: PDCD10,CCM3,TFAR15

Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID: 11235

UniProt: Q9BUL8