Peroxiredoxin 2 antibody

Catalog No. ABIN6989865

The Rabbit Polyclonal anti-Peroxiredoxin 2 antibody (ABIN6989865) specifically detects Peroxiredoxin 2 in WB, IF and IF (cc). The antibody is reactive with Human samples.

Quick Overview for Peroxiredoxin 2 antibody (ABIN6989865)

Target: Peroxiredoxin 2 (PRDX2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Peroxiredoxin 2 Antibody

Purpose: PRDX2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX2 (NP_859428.1).

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(ICC)(1:50-200), IF(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Alternative Name: PRDX2

Background:

Synonyms: PRDX2,HEL-S-2a,NKEF-B,NKEFB,PRP,PRX2,PRXII,PTX1,TDPX1,TPX1,TSA

Background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Gene ID: 7001

UniProt: P32119