Histone H1.3+Histone H1.4 (pThr17) antibody

Catalog No. ABIN6989919

The Rabbit Monoclonal anti-Histone H1.3+Histone H1.4 antibody (Clone 5H3) (ABIN6989919) specifically detects Histone H1.3+Histone H1.4 in IHC, WB, IF (cc) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Histone H1.3+Histone H1.4 (pThr17) antibody (ABIN6989919)

Target: Histone H1.3+Histone H1.4

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5H3

Product Details

Binding Specificity: pThr17

Purpose: Phospho-Histone H1.3(T17)+Histone H1.4(T17) Monoclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic phospho-Peptide corresponding to residues surrounding Thr17 of human H1.4.

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IF(ICC)(1:50-200), IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Histone H1.3+Histone H1.4

Background:

Synonyms: Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1DH1F3, Histone H1.4, Histone H1b, Histone H1s-4, HIST1H1EH1F4

Background: Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Gene ID: 3008

UniProt: P10412