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IRF3 antibody (pSer386)

The Rabbit Monoclonal anti-IRF3 antibody has been validated for WB and IF (cc). It is suitable to detect IRF3 in samples from Human.
Catalog No. ABIN6989927

Quick Overview for IRF3 antibody (pSer386) (ABIN6989927)

Target

See all IRF3 Antibodies
IRF3 (Interferon Regulatory Factor 3 (IRF3))

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This IRF3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone

6H4
  • Binding Specificity

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    pSer386

    Cross-Reactivity

    Human

    Purification

    Purified by Protein A.

    Immunogen

    Synthetic phospho-Peptide corresponding to residues surrounding Ser386 of human IRF3.

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C for 12 months.

    Expiry Date

    12 months
  • Target

    IRF3 (Interferon Regulatory Factor 3 (IRF3))

    Alternative Name

    IRF3

    Background

    Synonyms: IIAE7 antibody, Interferon regulatory factor 3 antibody, IRF 3 antibody, IRF-3 antibody, IRF3 antibody, IRF3_HUMAN antibody, MGC94729 antibody

    Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

    Gene ID

    3661

    UniProt

    Q14653

    Pathways

    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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