Hemagglutinin antibody

Catalog No. ABIN6990168

This anti-Hemagglutinin antibody is a Mouse Monoclonal antibody detecting Hemagglutinin in ELISA. Suitable for Influenza A Virus H5N1.

Quick Overview for Hemagglutinin antibody (ABIN6990168)

Target: Hemagglutinin (HA)

Reactivity: Influenza A Virus H5N1

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hemagglutinin antibody is un-conjugated

Application: ELISA

Clone: 4F1F2

Product Details anti-Hemagglutinin Antibody

Purification: Hemagglutinin Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Immunogen: A peptide corresponding to synthetic peptide corresponding to 14 amino acids in the middle of Hemagglutinin.

Isotype: IgG3

Application Details

Application Notes: Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μ,g/mL. Other applications are pending.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Hemagglutinin Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Hemagglutinin monoclonal antibody can be stored at -20°C, stable for one year.

Target Details for Hemagglutinin

Target: Hemagglutinin (HA)

Alternative Name: Hemagglutinin

Target Type: Influenza Protein

Background: Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.

UniProt: Q692M2