CXCR6 antibody (C-Term)

Catalog No. ABIN6990265

Product Details anti-CXCR6 Antibody

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Bonzo Antibody is Antibody is DEAE purified.

Immunogen: Bonzo antibody was raised against a 20 amino acid peptide near the carboxy terminus of human Bonzo. The immunogen is located within the last 50 amino acids of Bonzo.

Isotype: IgG

Application Details

Application Notes: Bonzo antibody can be used for detection of Bonzo by Western blot at 1:1000 dilution.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Bonzo Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Bonzo antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Alternative Name: Bonzo (CXCR6 Products)

Synonyms: BONZO antibody, CD186 antibody, STRL33 antibody, TYMSTR antibody, BB217514 antibody, C-X-C motif chemokine receptor 6 antibody, chemokine (C-X-C motif) receptor 6 L homeolog antibody, chemokine (C-X-C motif) receptor 6 antibody, CXCR6 antibody, cxcr6.L antibody, Cxcr6 antibody

Background: Bonzo Antibody: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.

Gene ID: 10663

UniProt: O00574