FAIM2 antibody (N-Term)

Catalog No. ABIN6990340

This Rabbit Polyclonal antibody specifically detects FAIM2 in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FAIM2 antibody (N-Term) (ABIN6990340)

Target: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAIM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FAIM2 Antibody

Binding Specificity: N-Term

Purification: FAIM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: FAIM2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human FAIM2. The immunogen is located within the first 50 amino acids of FAIM2.

Isotype: IgG

Application Details

Application Notes: FAIM2 antibody can be used for detection of FAIM2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FAIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FAIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FAIM2

Target: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Alternative Name: FAIM2

Background: FAIM2 Antibody: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.

Gene ID: 23017

UniProt: Q9BWQ8