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KAP1 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects KAP1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN6990391

Quick Overview for KAP1 antibody (C-Term) (ABIN6990391)

Target

See all KAP1 (TRIM28) Antibodies
KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Reactivity

  • 114
  • 54
  • 52
  • 10
  • 10
  • 9
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 117
  • 17
  • 4
Rabbit

Clonality

  • 108
  • 30
Polyclonal

Conjugate

  • 72
  • 8
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This KAP1 antibody is un-conjugated

Application

  • 91
  • 48
  • 41
  • 28
  • 27
  • 26
  • 26
  • 25
  • 20
  • 20
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 23
    • 15
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificity

    At least three isoforms of TRIM28 are known to exist, this antibody will detect all three isoforms

    Purification

    TRIM28 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    Rabbit polyclonal TRIM28 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TRIM28. The immunogen is located within the last 50 amino acids of TRIM28.

    Isotype

    IgG
  • Application Notes

    TRIM28 antibody can be used for detection of TRIM28 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    TRIM28 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,4 °C

    Storage Comment

    TRIM28 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target

    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

    Alternative Name

    TRIM28

    Background

    TRIM28 Antibody: TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation.

    Molecular Weight

    Predicted: 92 kDa

    Gene ID

    10155

    NCBI Accession

    NP_005753

    UniProt

    Q13263

    Pathways

    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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