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TLR7 antibody (AA 420-470)

This Rabbit Polyclonal antibody specifically detects TLR7 in WB, ELISA and ICC. It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN6990451

Quick Overview for TLR7 antibody (AA 420-470) (ABIN6990451)

Target

See all TLR7 Antibodies
TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity

  • 95
  • 44
  • 9
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 92
  • 20
Rabbit

Clonality

  • 80
  • 31
  • 1
Polyclonal

Conjugate

  • 67
  • 8
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
This TLR7 antibody is un-conjugated

Application

  • 64
  • 48
  • 33
  • 18
  • 14
  • 10
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • Binding Specificity

    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-470

    Purification

    TLR7 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7. The immunogen is located within amino acids 420 - 470 of TLR7.

    Isotype

    IgG
  • Application Notes

    TLR7 antibody can be used for detection of TLR7 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    TLR7 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,4 °C

    Storage Comment

    TLR7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    TLR7 (Toll-Like Receptor 7 (TLR7))

    Alternative Name

    TLR7

    Background

    TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.

    Molecular Weight

    Predicted: 116 kDa

    Observed: 135 kDa

    Gene ID

    170743

    NCBI Accession

    NP_573474

    UniProt

    P58681

    Pathways

    TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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