TRPC3 antibody (C-Term)

Catalog No. ABIN6990670

Product Details anti-TRPC3 Antibody

Target: TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))

Binding Specificity: AA 760-810, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: TRPC3 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRPC3 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TRPC3. The immunogen is located within amino acids 760 - 810 of TRPC3.

Isotype: IgG

Application Details

Application Notes: TRPC3 antibody can be used for the detection of TRPC3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRPC3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TRPC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TRPC3

Target: TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))

Alternative Name: TRPC3 (TRPC3 Products)

Synonyms: TRPC3 antibody, Trpc3 antibody, TRP3 antibody, Mwk antibody, Trcp3 antibody, Trp3 antibody, Trrp3 antibody, TrpC3c antibody, transient receptor potential cation channel subfamily C member 3 antibody, transient receptor potential cation channel, subfamily C, member 3 antibody, TRPC3 antibody, Trpc3 antibody

Background: TRPC3 Antibody: The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

Gene ID: 7222

UniProt: Q13507