TARBP2 antibody (AA 1310-1360)

Catalog No. ABIN6990701

Product Details anti-TARBP2 Antibody

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Binding Specificity: AA 1310-1360

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: TRBP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRBP1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1. The immunogen is located within amino acids 1310 - 1360 of TRBP1.

Isotype: IgG

Application Details

Application Notes: TRBP1 antibody can be used for detection of TRBP1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRBP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TRBP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TARBP2

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Alternative Name: TRBP1 (TARBP2 Products)

Synonyms: trbp antibody, trbp1 antibody, trbp2 antibody, MGC97783 antibody, TARBP2 antibody, LOQS antibody, TRBP antibody, TRBP1 antibody, TRBP2 antibody, fj51e12 antibody, wu:fj51e12 antibody, zgc:63778 antibody, Prbp antibody, TAR (HIV-1) RNA binding protein 2 antibody, TARBP2, RISC loading complex RNA binding subunit antibody, TAR (HIV-1) RNA binding protein 2 L homeolog antibody, TAR (HIV) RNA binding protein 2 antibody, tarbp2 antibody, TARBP2 antibody, tarbp2.L antibody, Tarbp2 antibody

Background: TRBP1 Antibody: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1α, (EF-1α,), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

Gene ID: 6894

NCBI Accession: NP_005637

UniProt: Q13395

Pathways: Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization