CX3CR1 antibody (N-Term)

Catalog No. ABIN6990706

This Rabbit Polyclonal antibody specifically detects CX3CR1 in WB, FACS, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CX3CR1 antibody (N-Term) (ABIN6990706)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CX3CR1 Antibody

Binding Specificity: N-Term

Purification: CX3CR1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-CX3CR1 antibody was raised against a peptide corresponding to 20 amino acids near the amino terminus of mature human CX3CR1. The immunogen is located within the first 50 amino acids of CX3CR1.

Isotype: IgG

Application Details

Application Notes: WB: 1 -2 μ,g/mL, IF: 10-20 μ,g/mL, IHC-P: 2 μ,g/mL: Flow: 0.1 μ,g/mL .

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in rat samples, Immunofluorescence in human, mouse and rat samples, Flow cytometry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CX3CR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CX3CR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1

Background: CX3CR1 Antibody: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.

Molecular Weight: Predicted: 40-44 kD

Observed: 50 kD kDa

Gene ID: 1524

NCBI Accession: NP_001328

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin