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Stim2 antibody (C-Term)

Stim2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990745
  • Target See all Stim2 Antibodies
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 13
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 1
    • 1
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    This Stim2 antibody is un-conjugated
    Application
    • 33
    • 26
    • 19
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    STIM2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    STIM2 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STIM2. The immunogen is located within the last 50 amino acids of STIM2.
    Isotype
    IgG
    Top Product
    Discover our top product Stim2 Primary Antibody
  • Application Notes
    STIM2 antibody can be used for detection of STIM2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    STIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    STIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Alternative Name
    STIM2 (Stim2 Products)
    Synonyms
    STIM2 antibody, stromal interaction molecule 2 antibody, STIM2 antibody, stim2 antibody, Stim2 antibody
    Background
    STIM2 Antibody: In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.
    Gene ID
    57620
    NCBI Accession
    NP_065911
    UniProt
    Q9P246
    Pathways
    TCR Signaling, BCR Signaling
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