TBC1D4 antibody (C-Term)

Catalog No. ABIN6990834

The Rabbit Polyclonal anti-TBC1D4 antibody (ABIN6990834) specifically detects TBC1D4 in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TBC1D4 antibody (C-Term) (ABIN6990834)

Target: TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TBC1D4 Antibody

Binding Specificity: AA 1190-1240, C-Term

Purification: TBC1D4 Antibody is affinity chromatography purified via peptide column.

Immunogen: TBC1D4 antibody was raised against an 19 amino acid peptide near the carboxy terminus of human TBC1D4 . The immunogen is located within amino acids 1190 - 1240 of TBC1D4.

Isotype: IgG

Application Details

Application Notes: TBC1D4 antibody can be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TBC1D4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TBC1D4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TBC1D4

Target: TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))

Alternative Name: TBC1D4

Background: TBC1D4 Antibody: TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes.

Molecular Weight: Predicted: 143 kDa

Observed: 140 kDa

Gene ID: 9882

NCBI Accession: NP_055647

UniProt: O60343