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PLXDC2 antibody (N-Term)

PLXDC2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990835
  • Target See all PLXDC2 Antibodies
    PLXDC2 (Plexin Domain Containing 2 (PLXDC2))
    Binding Specificity
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-90, N-Term
    Reactivity
    • 14
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 12
    • 2
    Rabbit
    Clonality
    • 12
    • 2
    Polyclonal
    Conjugate
    • 14
    This PLXDC2 antibody is un-conjugated
    Application
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    Plxdc2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Plxdc2 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human Plxdc2. The immunogen is located within amino acids 40 - 90 of Plxdc2.
    Isotype
    IgG
    Top Product
    Discover our top product PLXDC2 Primary Antibody
  • Application Notes
    Plxdc2 antibody can be used for detection of Plxdc2 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Plxdc2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    Plxdc2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PLXDC2 (Plexin Domain Containing 2 (PLXDC2))
    Alternative Name
    Plxdc2 (PLXDC2 Products)
    Synonyms
    MGC79122 antibody, TEM7R antibody, 1200007L24Rik antibody, 5430431D22Rik antibody, AI646728 antibody, AU022916 antibody, AV231634 antibody, Tem7r antibody, plexin domain containing 2 antibody, plexin domain containing 2 L homeolog antibody, PLXDC2 antibody, plxdc2.L antibody, plxdc2 antibody, Plxdc2 antibody
    Background
    Plxdc2 Antibody: Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57 % amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.
    Molecular Weight
    Predicted: 55 kDa

    Observed: 55 kDa
    Gene ID
    84898
    UniProt
    Q6UX71
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