SLITRK2 antibody (AA 650-700)

Catalog No. ABIN6990852

Product Details anti-SLITRK2 Antibody

Target: SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))

Binding Specificity: AA 650-700

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Purification: Slitrk2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Slitrk2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human Slitrk2. The immunogen is located within amino acids 650 - 700 of Slitrk2.

Isotype: IgG

Application Details

Application Notes: Slitrk2 antibody can be used for detection of Slitrk2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Slitrk2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Slitrk2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLITRK2

Target: SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))

Alternative Name: Slitrk2 (SLITRK2 Products)

Synonyms: slitrk2 antibody, CXorf2 antibody, SLITL1 antibody, A930040J07 antibody, RGD1561361 antibody, SLIT and NTRK-like family, member 2 antibody, SLIT and NTRK like family member 2 antibody, SLITRK2 antibody, slitrk2 antibody, Slitrk2 antibody

Background: Slitrk2 Antibody: SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.

Gene ID: 84631

UniProt: Q9H156