CUEDC1 antibody (C-Term)

Catalog No. ABIN6990989

The Rabbit Polyclonal anti-CUEDC1 antibody is suitable to detect CUEDC1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and IF.

Quick Overview for CUEDC1 antibody (C-Term) (ABIN6990989)

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUEDC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-CUEDC1 Antibody

Binding Specificity: AA 310-360, C-Term

Specificity: CUEDC1 antibody will not cross-react with CUEDC2.

Purification: CUEDC1 Antibody is affinity chromatography purified via peptide column.

Immunogen: CUEDC1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CUEDC1. The immunogen is located within amino acids 310 - 360 of CUEDC1.

Isotype: IgG

Application Details

Application Notes: CUEDC1 antibody can be used for detection of CUEDC1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CUEDC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CUEDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CUEDC1

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Alternative Name: CUEDC1

Background: CUEDC1 Antibody: The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.

Gene ID: 404093

UniProt: Q9NWM3