METTL7B antibody (N-Term)

Catalog No. ABIN6991014

This anti-METTL7B antibody is a Rabbit Polyclonal antibody detecting METTL7B in WB, ELISA and IHC (p). Suitable for Human and Mouse.

Quick Overview for METTL7B antibody (N-Term) (ABIN6991014)

Target: METTL7B (Methyltransferase Like 7B (METTL7B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-METTL7B Antibody

Binding Specificity: AA 20-70, N-Term

Specificity: This MettL7B antibody is predicted to not cross-react with MettL7A.

Purification: MettL7B Antibody is affinity chromatography purified via peptide column.

Immunogen: MettL7B antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human MettL7B. The immunogen is located within amino acids 20 - 70 of MettL7B.

Isotype: IgG

Application Details

Application Notes: MettL7b antibody can be used for detection of mettl7b by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MettL7B Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MettL7B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for METTL7B

Target: METTL7B (Methyltransferase Like 7B (METTL7B))

Alternative Name: MettL7B

Background: MettL7B Antibody: MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Molecular Weight: Predicted: 27 kDa

Observed: 27 kDa

Gene ID: 196410

NCBI Accession: NP_689850

UniProt: Q6UX53