SCARA5 antibody (C-Term)

Catalog No. ABIN6991153

This Rabbit Polyclonal antibody specifically detects SCARA5 in ELISA, WB, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for SCARA5 antibody (C-Term) (ABIN6991153)

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARA5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-SCARA5 Antibody

Binding Specificity: AA 350-400, C-Term

Specificity: At least four isoforms of SCARA5 are known to exist, this antibody will detect all four isoforms.

Purification: SCARA5 Antibody is affinity chromatography purified via peptide column.

Immunogen: SCARA5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SCARA5. The immunogen is located within amino acids 350 - 400 of SCARA5.

Isotype: IgG

Application Details

Application Notes: SCARA5 antibody can be used for detection of SCARA5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SCARA5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SCARA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SCARA5

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Alternative Name: SCARA5

Background: SCARA5 Antibody: Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains the collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery.

Molecular Weight: Predicted: 24, 39, 44, 54 kDa

Observed: 50 kDa

Gene ID: 286133

NCBI Accession: NP_776194

UniProt: Q6ZMJ2

Pathways: Transition Metal Ion Homeostasis