SYPL1 antibody (N-Term)

Catalog No. ABIN6991164

The Rabbit Polyclonal anti-SYPL1 antibody (ABIN6991164) specifically detects SYPL1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SYPL1 antibody (N-Term) (ABIN6991164)

Target: SYPL1 (Synaptophysin-Like 1 (SYPL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYPL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SYPL1 Antibody

Binding Specificity: N-Term

Specificity: This antibody will not recognize synaptophysin of SYPL2. Two isoforms of SYPL1 are known to exist, this antibody will only recognize the longer isoform.

Purification: SYPL1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SYPL1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SYPL1. The immunogen is located within the first 50 amino acids of SYPL1.

Isotype: IgG

Application Details

Application Notes: SYPL1 antibody can be used for detection of SYPL1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SYPL1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SYPL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SYPL1

Target: SYPL1 (Synaptophysin-Like 1 (SYPL1))

Alternative Name: SYPL1

Background: SYPL1 Antibody: The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles.

Gene ID: 6856

NCBI Accession: NP_006745

UniProt: Q16563