FAM120B antibody (C-Term)

Catalog No. ABIN6991173

Product Details anti-FAM120B Antibody

Target: FAM120B (Family with Sequence Similarity 120B (FAM120B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM120B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody will not cross-react with FAM120A.

Purification: PGCC1 Antibody is affinity chromatography purified via peptide column.

Immunogen: PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1. The immunogen is located within the last 50 amino acids of PGCC1.

Isotype: IgG

Application Details

Application Notes: PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PGCC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PGCC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FAM120B

Target: FAM120B (Family with Sequence Similarity 120B (FAM120B))

Alternative Name: PGCC1 (FAM120B Products)

Synonyms: 4932442K08Rik antibody, AW049283 antibody, AW413338 antibody, CCPG antibody, Pgcc1 antibody, mKIAA1838 antibody, KIAA1838 antibody, PGCC1 antibody, dJ894D12.1 antibody, RGD1310304 antibody, family with sequence similarity 120B antibody, family with sequence similarity 120, member B antibody, FAM120B antibody, Fam120b antibody

Background: PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.

Gene ID: 84498

UniProt: Q96EK7