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FRMPD2 antibody (N-Term)

FRMPD2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991212
  • Target See all FRMPD2 Antibodies
    FRMPD2 (FERM and PDZ Domain Containing 2 (FRMPD2))
    Binding Specificity
    • 2
    • 2
    • 1
    AA 80-130, N-Term
    Reactivity
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 3
    • 2
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This FRMPD2 antibody is un-conjugated
    Application
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    FRMPD2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    FRMPD2 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FRMPD2. The immunogen is located within amino acids 80 - 130 of FRMPD2.
    Isotype
    IgG
    Top Product
    Discover our top product FRMPD2 Primary Antibody
  • Application Notes
    FRMPD2 antibody can be used for detection of FRMPD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    FRMPD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    FRMPD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    FRMPD2 (FERM and PDZ Domain Containing 2 (FRMPD2))
    Alternative Name
    FRMPD2 (FRMPD2 Products)
    Synonyms
    Frmpd2 antibody, Gm1582 antibody, ENSMUSG00000071536 antibody, FRMPD2 antibody, PDZD5C antibody, PDZK4 antibody, PDZK5C antibody, FERM and PDZ domain containing 2 antibody, putative protein FRMPD2-like antibody, FERM and PDZ domain-containing protein 2 antibody, Frmpd2 antibody, FRMPD2 antibody, LOC100051923 antibody, LOC100348282 antibody, LOC100548446 antibody
    Background
    FRMPD2 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD2 also contains an N-terminal KIND domain and three PDZ domains and is structurally similar to the protein tyrosine phosphatase PTP-BL. FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially co-localizes with the tight-junction marker protein Zonula-occuldens-1. Suppression of FRMPD2 expression via RNAi in Caco-2 cells results in an impairment of tight junction formation, indicating that FRMPD2 plays a major role in tight junction formation. Other experiments indicate that FRMPD2 is a binding partner to several catenin family members and recruitment of FRMPD2 to cell-cell contacts is dependent on E-cadherin-mediated cell-cell adhesion.
    Gene ID
    143162
    NCBI Accession
    NP_001018081
    UniProt
    Q68DX3
    Pathways
    Cell-Cell Junction Organization
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