SLAIN2 antibody (N-Term)

Catalog No. ABIN6991219

Product Details anti-SLAIN2 Antibody

Target: SLAIN2 (SLAIN Motif Family, Member 2 (SLAIN2))

Binding Specificity: AA 70-120, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAIN2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: SLAIN2 antibody is predicted not to cross-react with SLAIN1.

Purification: SLAIN2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SLAIN2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human SLAIN2. The immunogen is located within amino acids 70 - 120 of SLAIN2.

Isotype: IgG

Application Details

Application Notes: SLAIN2 antibody can be used for detection of SLAIN2 by immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLAIN2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SLAIN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLAIN2

Target: SLAIN2 (SLAIN Motif Family, Member 2 (SLAIN2))

Alternative Name: SLAIN2 (SLAIN2 Products)

Synonyms: KIAA1458 antibody, 5033405K12Rik antibody, 8030444K12Rik antibody, AI596370 antibody, mKIAA1458 antibody, RGD1311593 antibody, si:dkey-90m5.3 antibody, SLAIN motif family member 2 antibody, SLAIN motif family, member 2 antibody, SLAIN2 antibody, Slain2 antibody, slain2 antibody

Background: SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.

Molecular Weight: 64 kDa

Gene ID: 57606

UniProt: Q9P270