SIPA1L2 antibody (N-Term)

Catalog No. ABIN6991228

This Rabbit Polyclonal antibody specifically detects SIPA1L2 in ELISA, WB, IHC (p) and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SIPA1L2 antibody (N-Term) (ABIN6991228)

Target: SIPA1L2 (Signal-Induced Proliferation-Associated 1 Like 2 (SIPA1L2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIPA1L2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-SIPA1L2 Antibody

Binding Specificity: N-Term

Purification: SIPA1L2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SIPA1L2 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1L2. The immunogen is located within the first 50 amino acids of SIPA1L2.

Isotype: IgG

Application Details

Application Notes: SIPA1L2 antibody can be used for detection of SIPA1L2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIPA1L2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SIPA1L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SIPA1L2

Target: SIPA1L2 (Signal-Induced Proliferation-Associated 1 Like 2 (SIPA1L2))

Alternative Name: SIPA1L2

Background: SIPA1L2 Antibody: Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.

Gene ID: 57568

NCBI Accession: NP_065859

UniProt: Q9P2F8