PPAPDC1A antibody (C-Term)

Catalog No. ABIN6991235

The Rabbit Polyclonal anti-PPAPDC1A antibody is suitable to detect PPAPDC1A in samples from Mouse, Human and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for PPAPDC1A antibody (C-Term) (ABIN6991235)

Target: PPAPDC1A (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1A (PPAPDC1A))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAPDC1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-PPAPDC1A Antibody

Binding Specificity: C-Term

Purification: PPAPDC1A Antibody is affinity chromatography purified via peptide column.

Immunogen: PPAPDC1A antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human PPAPDC1A. The immunogen is located within the last 50 amino acids of PPAPDC1A.

Isotype: IgG

Application Details

Application Notes: PPAPDC1A antibody can be used for detection of PPAPDC1A by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PPAPDC1A Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PPAPDC1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PPAPDC1A

Target: PPAPDC1A (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1A (PPAPDC1A))

Alternative Name: PPAPDC1A

Background: PPAPDC1A Antibody: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.

Gene ID: 196051

NCBI Accession: NP_001025230

UniProt: Q5VZY2