SIRT7 antibody (N-Term)

Catalog No. ABIN6991348

This Chicken Polyclonal antibody specifically detects SIRT7 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for SIRT7 antibody (N-Term) (ABIN6991348)

Target: SIRT7 (Sirtuin 7 (SIRT7))

Reactivity: Human, Rat, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This SIRT7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRT7 Antibody

Binding Specificity: AA 50-100, N-Term

Purification: SIRT7 Antibody is affinity chromatography purified via peptide column.

Immunogen: SIRT7 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SIRT7. The immunogen is located within amino acids 50 - 100 of SIRT7.

Isotype: IgY

Application Details

Application Notes: SIRT7 antibody can be used for detection of SIRT7 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIRT7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SIRT7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SIRT7

Target: SIRT7 (Sirtuin 7 (SIRT7))

Alternative Name: SIRT7

Background: SIRT7 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.

Gene ID: 51547

NCBI Accession: NP_057622

UniProt: Q9NRC8