Calneuron 1 antibody (N-Term)

Catalog No. ABIN6991382

Product Details anti-Calneuron 1 Antibody

Target: Calneuron 1 (CALN1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calneuron 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: CaBP8 Antibody is affinity chromatography purified via peptide column.

Immunogen: CaBP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CaBP8. The immunogen is located within the first 50 amino acids of CaBP8.

Isotype: IgG

Application Details

Application Notes: CaBP8 antibody can be used for detection of CaBP8 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CaBP8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CaBP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Calneuron 1

Target: Calneuron 1 (CALN1)

Alternative Name: CaBP8 (CALN1 Products)

Synonyms: CALN1 antibody, CABP8 antibody, 9630012C17Rik antibody, Cabp8 antibody, calneuron 1 antibody, CALN1 antibody, caln1 antibody, Caln1 antibody

Background: CaBP8 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70 % homology with CaBP7 and 50 % homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Gene ID: 83698

NCBI Accession: NP_113656

UniProt: Q9BXU9