SESTD1 antibody (C-Term)

Catalog No. ABIN6991390

Product Details anti-SESTD1 Antibody

Target: SESTD1 (SEC14 and Spectrin Domains 1 (SESTD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESTD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: SESTD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SESTD1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SESTD1. The immunogen is located within the last 50 amino acids of SESTD1.

Isotype: IgG

Application Details

Application Notes: SESTD1 antibody can be used for detection of SESTD1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SESTD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SESTD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SESTD1

Target: SESTD1 (SEC14 and Spectrin Domains 1 (SESTD1))

Alternative Name: SESTD1 (SESTD1 Products)

Synonyms: SOLO antibody, 1500031J16Rik antibody, A930010O20 antibody, Solo/Trio8 antibody, RGD1562244 antibody, sestd1-A antibody, SEC14 and spectrin domain containing 1 antibody, SEC14 and spectrin domains 1 antibody, SEC14 and spectrin domain containing 1 S homeolog antibody, SESTD1 antibody, sestd1 antibody, Sestd1 antibody, sestd1.S antibody

Background: SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.

Gene ID: 91404

NCBI Accession: NP_835224

UniProt: Q86VW0