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NLRC3 antibody (AA 630-680)

NLRC3 Reactivity: Human, Mouse, Rat WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991397
  • Target See all NLRC3 Antibodies
    NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
    Binding Specificity
    • 1
    • 1
    • 1
    AA 630-680
    Reactivity
    Human, Mouse, Rat
    Host
    • 3
    • 1
    Rabbit
    Clonality
    • 3
    • 1
    Polyclonal
    Conjugate
    • 4
    This NLRC3 antibody is un-conjugated
    Application
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    NOD3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    NOD3 antibody was raised against an 18 amino acid synthetic peptide near the center of human NOD3. The immunogen is located within amino acids 630 - 680 of NOD3.
    Isotype
    IgG
    Top Product
    Discover our top product NLRC3 Primary Antibody
  • Application Notes
    NOD3 antibody can be used for detection of NOD3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    NOD3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    NOD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
    Alternative Name
    NOD3 (NLRC3 Products)
    Synonyms
    NLRC3 antibody, nod3 antibody, NLR-A3 antibody, NOD3 antibody, CLR16.2 antibody, D230007K08Rik antibody, mFLJ00348 antibody, Nlrc3-ps1 antibody, RGD1304902 antibody, NLR family CARD domain containing 3 antibody, NLR family, CARD domain containing 3 antibody, NLRC3 antibody, nlrc3 antibody, Nlrc3 antibody
    Background
    NOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
    Gene ID
    197358
    UniProt
    Q7RTR2
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