TCF12 antibody (N-Term)

Catalog No. ABIN6991422

This anti-TCF12 antibody is a Rabbit Polyclonal antibody detecting TCF12 in WB, ELISA and ICC. Suitable for Human, Rat and Mouse.

Quick Overview for TCF12 antibody (N-Term) (ABIN6991422)

Target: TCF12 (Transcription Factor 12 (TCF12))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-TCF12 Antibody

Binding Specificity: AA 50-100, N-Term

Purification: TCF12 Antibody is affinity chromatography purified via peptide column.

Immunogen: TCF12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCF12. The immunogen is located within amino acids 50 - 100 of TCF12.

Isotype: IgG

Application Details

Application Notes: TCF12 antibody can be used for detection of TCF12 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TCF12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TCF12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TCF12

Target: TCF12 (Transcription Factor 12 (TCF12))

Alternative Name: TCF12

Background: TCF12 Antibody: TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

Gene ID: 6938

UniProt: Q99081

Pathways: SARS-CoV-2 Protein Interactome