OGFOD1 antibody (C-Term)
Quick Overview for OGFOD1 antibody (C-Term) (ABIN6991486)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist, this antibody will only detect the larger isform.
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Purification
- OGFOD1 Antibody is affinity chromatography purified via peptide column.
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Immunogen
- OGFOD1 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human OGFOD1. The immunogen is located within the first 50 amino acids of OGFOD1.
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Isotype
- IgG
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Application Notes
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OGFOD1 antibody can be used for detection of OGFOD1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- OGFOD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,4 °C
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Storage Comment
- OGFOD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- OGFOD1 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 1 (OGFOD1))
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Alternative Name
- OGFOD1
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Background
- OGFOD1 Antibody: OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
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Gene ID
- 55239
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NCBI Accession
- NP_060703
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UniProt
- Q8N543
Target
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